The sort button is right next to the close button in the inventory window, and depending on your resolution both can be quite tiny. Every time I accidentally hit the sort button I lose 10 minutes of my life to carefully rearranging my sacks and items just as I like to keep them. It would be very nice to have an option to disable the sort button, or at least simply space the three buttons further apart.
Yes, I know pressing "i" will close the window so I'll try to train myself to do that, but I'm a natural clicker.
Anyhow, there's no reason for the buttons to be so small and be spaced so closely together.